The Huberman Lab Podcast discusses neuroscience: how our brain and its connections with the organs of our body control our perceptions, our behaviors, and our health. We also discuss existing and emerging tools for measuring and changing how our nervous system works. Dr. Andrew Huberman is a tenured Professor of Neurobiology and Ophthalmology at Stanford School of Medicine. His laboratory studies neural regeneration, neuroplasticity, and brain states such as stress, focus, fear, and optimal performance. For more than 20 years, Dr. Huberman has consistently published original research findings and review articles in top-level peer-reviewed journals, including Nature, Science, Cell, Neuron, and Current Biology. He is a regular member of several National Institutes of Health review panels and a Fellow of the McKnight Foundation and the Pew Charitable Trusts. Dr. Huberman regularly consults for technology development companies, professional athletic organizations, and various units of U.S. and Canadian Special Operations.

Essentials: Breathing for Mental & Physical Health & Performance | Dr. Jack Feldman

November 13, 2025 0:49:45 9.2 MB ( -9.21 MB less) Downloads: 0

In this Huberman Lab Essentials episode, my guest is Dr. Jack Feldman, PhD, a Distinguished Professor of Neurobiology at the University of California, Los Angeles, and a leading expert in the science of breathing.

We explain the mechanics of breathing and the neural circuits that generate and regulate our breathing rhythm. We also discuss how breathing patterns profoundly influence mental states, including their role in reducing anxiety and enhancing emotional resilience. Dr. Feldman also shares practical tools, such as box breathing for daily performance and magnesium L-threonate supplementation to support cognitive health and longevity.

Read the episode show notes at hubermanlab.com.

Thank you to our sponsors

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Timestamps

00:00:00 Jack Feldman

00:00:23 Breathing Mechanics, Diaphragm; Pre-Bötzinger Complex & Breath Initiation

00:03:25 Nose vs Mouth Breathing

00:04:23 Sponsor: Mateina

00:05:24 Active Expiration & Brain; Retrotrapezoid Nucleus

00:08:32 Diaphragm & Evolution; Lung Surface Area & Alveoli, Oxygen Exchange

00:12:56 Diaphragmatic vs Non-Diaphragmatic Breathing

00:14:23 Physiological Sighs: Frequency & Function; Polio & Ventilators

00:18:21 Sponsor: AGZ by AG1

00:19:52 Drug Overdose, Death & Gasps

00:21:38 Meditation, Slow Breathing & Fear Conditioning Study

00:25:28 Mechanistic Science in Breathwork Validation; Breath Practice & Reduced Fear

00:27:21 Breathing & Emotional/Cognitive State, Olfaction, Vagus Nerve

00:29:44 Carbon Dioxide, Hyperventilation & Anxiety

00:31:21 Sponsor: Eight Sleep

00:32:47 Breathing, Emotion & Autonomic Processes Coordination; Depression & Breath Practices

00:36:43 Tool: Breathwork Practices, Box Breathing, Tummo, Wim Hof

00:38:46 Magnesium L-Threonate & Cognitive Enhancement; Compound Refinement

00:44:28 Clinical Trial, Magnesium L-Threonate & Cognitive Improvements; Dose, Sleep

00:48:28 Acknowledgements

Disclaimer & Disclosures

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