The Huberman Lab Podcast discusses neuroscience: how our brain and its connections with the organs of our body control our perceptions, our behaviors, and our health. We also discuss existing and emerging tools for measuring and changing how our nervous system works. Dr. Andrew Huberman is a tenured Professor of Neurobiology and Ophthalmology at Stanford School of Medicine. His laboratory studies neural regeneration, neuroplasticity, and brain states such as stress, focus, fear, and optimal performance. For more than 20 years, Dr. Huberman has consistently published original research findings and review articles in top-level peer-reviewed journals, including Nature, Science, Cell, Neuron, and Current Biology. He is a regular member of several National Institutes of Health review panels and a Fellow of the McKnight Foundation and the Pew Charitable Trusts. Dr. Huberman regularly consults for technology development companies, professional athletic organizations, and various units of U.S. and Canadian Special Operations.

Essentials: How to Build, Maintain & Repair Gut Health | Dr. Justin Sonnenburg

December 11, 2025 0:39:12 6.83 MB ( -6.84 MB less) Downloads: 0

In this Huberman Lab Essentials episode, my guest is Dr. Justin Sonnenburg, PhD, a professor of microbiology and immunology at Stanford University.

We discuss how microbes in our gut impact our mental and physical health and how diet and the environment affect the gut microbiome. We explain how lifestyle factors such as antibiotics and Western-style diets (high fat, low fiber and rich in processed foods) can damage gut diversity and whether prebiotics or probiotics are useful tools. Throughout the episode, we highlight evidence-based dietary and lifestyle strategies for improving gut health.

Episode show notes: https://go.hubermanlab.com/VXfckJf

Thank you to our sponsors

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Timestamps

00:00:00 Justin Sonnenburg

00:00:20 What is the Microbiome?

00:02:55 Microbiome Origin, Babies, Environmental Factors

00:04:47 Healthy Microbiome, Individuality; Industrialized vs Traditional Populations

00:07:06 Sponsor: AG1

00:08:30 “Reprogramming” the Gut Microbiome; Antibiotics, Western Diet

00:12:58 Cleanses & Fasting

00:13:55 Processed Foods & Microbiome, Artificial Sweeteners, Emulsifiers

00:17:35 Sponsor: Joovv

00:18:55 Inflammatory Western Diseases, Microbiome & Immune System

00:21:51 Fiber, Fermented Foods & Microbiome, Tool: Fermented Food Consumption

00:28:20 Sponsor: Function

00:30:00 Fiber, Depleted Microbiome, Industrialization, Sanitation

00:31:33 Antibiotics, Over-Sanitation, Disease, Hand Washing

00:33:26 Probiotics, Tool: Product Validation,

00:35:15 Prebiotics, Tool: Plant Consumption

00:37:48 Good Gut Book, Justin’s Research

Disclaimer & Disclosures

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