The Huberman Lab Podcast discusses neuroscience: how our brain and its connections with the organs of our body control our perceptions, our behaviors, and our health. We also discuss existing and emerging tools for measuring and changing how our nervous system works. Dr. Andrew Huberman is a tenured Professor of Neurobiology and Ophthalmology at Stanford School of Medicine. His laboratory studies neural regeneration, neuroplasticity, and brain states such as stress, focus, fear, and optimal performance. For more than 20 years, Dr. Huberman has consistently published original research findings and review articles in top-level peer-reviewed journals, including Nature, Science, Cell, Neuron, and Current Biology. He is a regular member of several National Institutes of Health review panels and a Fellow of the McKnight Foundation and the Pew Charitable Trusts. Dr. Huberman regularly consults for technology development companies, professional athletic organizations, and various units of U.S. and Canadian Special Operations.
Essentials: Psychedelics & Neurostimulation for Brain Rewiring | Dr. Nolan Williams
In loving memory of Nolan Williams (1982-2025): https://stan.md/3Qle2zp
In this Huberman Lab Essentials episode, my guest is Dr. Nolan Williams, MD, a triple board-certified psychiatrist and neurologist. We discuss cutting-edge treatments for depression and post-traumatic stress disorder (PTSD), including transcranial magnetic stimulation, neuromodulation, and psychedelic-assisted therapies. We also discuss the neurobiology and therapeutic potential of specific psychedelic compounds, including psilocybin, MDMA, ibogaine, and ayahuasca.
Read the episode show notes at hubermanlab.com.
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Timestamps
(00:00:00) Nolan Williams
(00:00:21) Depression
(00:02:45) Heart & Mind Connection, Transcranial Magnetic Stimulation (TMS)
(00:05:15) TMS for Depression
(00:07:47) Sponsor: Function
(00:09:24) SSRIs & Chemical imbalance, TMS, Psychedelics
(00:15:24) Psilocybin, MDMA, Trauma
(00:18:21) MDMA Clinical Trials & PTSD; Psilocybin & Depression
(00:20:18) Sponsor: BetterHelp
(00:21:38) Psilocybin, Brain Connectivity & Depression
(00:23:59) Ibogaine, Empathy; Psychedelic Breakthrough & Risk
(00:30:36) Ayahuasca, Behavior Change, Prisoners
(00:34:46) Sponsor: AG1
(00:36:05) Stanford Accelerated Intelligent Neuromodulation Therapy (SAINT)
(00:40:07) Acknowledgements
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