The Huberman Lab Podcast discusses neuroscience: how our brain and its connections with the organs of our body control our perceptions, our behaviors, and our health. We also discuss existing and emerging tools for measuring and changing how our nervous system works. Dr. Andrew Huberman is a tenured Professor of Neurobiology and Ophthalmology at Stanford School of Medicine. His laboratory studies neural regeneration, neuroplasticity, and brain states such as stress, focus, fear, and optimal performance. For more than 20 years, Dr. Huberman has consistently published original research findings and review articles in top-level peer-reviewed journals, including Nature, Science, Cell, Neuron, and Current Biology. He is a regular member of several National Institutes of Health review panels and a Fellow of the McKnight Foundation and the Pew Charitable Trusts. Dr. Huberman regularly consults for technology development companies, professional athletic organizations, and various units of U.S. and Canadian Special Operations.
Bringing Extinct Species Back to Life | Dr. Beth Shapiro
Dr. Beth Shapiro, PhD, is an evolutionary biologist and Chief Science Officer at Colossal Biosciences. Her work focuses on de-extinction and wildlife conservation efforts. We discuss genetic differences among humans, and how ancient DNA and modern embryology are being used to de-extinct and protect woolly mammoths, dodo birds, and dire wolves, as well as to help conserve endangered species. We also explore the ethical implications of de-extinction and how synthetic biology can help build a more bio diverse and resilient world.
Read the full episode show notes at hubermanlab.com.
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Timestamps
(00:00:00) Beth Shapiro
(00:02:35) What is a Species?, Taxonomy, Bison
(00:09:13) Neanderthals, Denisovans, Homo Sapiens
(00:12:38) Sponsors: Joovv & Eight Sleep
(00:15:27) Hybrid Ancestry, “Grolar” Bears
(00:20:30) Homo Sapiens & Neanderthal Interbreeding, Genes; Denisovans
(00:25:53) Neanderthal Genes, Immunity, Red Hair; Eye Color
(00:30:17) De-Extinction, Species Selection, Woolly Mammoths
(00:38:08) Sponsor: AG1
(00:39:21) Bird De-Extinction, Dodo; Reproduction & Genes
(00:47:40) Development Biology, Woolly Mammoth, Elephants
(00:54:49) Dire Wolf, Synthetic Biology, Ethics
(01:03:26) De-Extinction, Ecology, Conservation, Ethics
(01:09:22) Ecosystem Resilience, Thylacine; Preventing Extinction, Quolls
(01:15:45) Sponsor: Function
(01:17:23) Modeling Ecological Impact, Mosquitoes, Gene Drives; Panthers
(01:25:50) Advisory Panels, Synthetic Biology Education
(01:29:13) Genetic Selection in Humans, Human-Shaped World
(01:38:25) Black-Footed Ferrets, Genetic Rescue
(01:47:05) Dire Wolf; Ecological Modeling, New Technology & Public Fear
(01:55:09) Artificial Wombs; Current Issues, Conservation & Red Wolf
(02:01:26) Science Pioneers; Colossal Public Education
(02:04:31) Beth’s Science Origin Story; Dinosaurs
(02:13:42) Zero-Cost Support, YouTube, Spotify & Apple Follow, Reviews & Feedback, Sponsors, Social Media, Neural Network Newsletter
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