The Huberman Lab Podcast discusses neuroscience: how our brain and its connections with the organs of our body control our perceptions, our behaviors, and our health. We also discuss existing and emerging tools for measuring and changing how our nervous system works. Dr. Andrew Huberman is a tenured Professor of Neurobiology and Ophthalmology at Stanford School of Medicine. His laboratory studies neural regeneration, neuroplasticity, and brain states such as stress, focus, fear, and optimal performance. For more than 20 years, Dr. Huberman has consistently published original research findings and review articles in top-level peer-reviewed journals, including Nature, Science, Cell, Neuron, and Current Biology. He is a regular member of several National Institutes of Health review panels and a Fellow of the McKnight Foundation and the Pew Charitable Trusts. Dr. Huberman regularly consults for technology development companies, professional athletic organizations, and various units of U.S. and Canadian Special Operations.
Dr. Robert Sapolsky: Science of Stress, Testosterone & Free Will | Episode 35
In this episode, I interview Dr. Robert Sapolsky, Ph.D., Professor of Biology, Neurology & Neurosurgery at Stanford University. We discuss stress, what defines short-term versus long-term stress, and how stress can be beneficial or detrimental, depending on the context. We also discuss stress mitigation and how our sense of control over stress mitigation techniques, including exercise, determine health outcomes. Dr. Sapolsky explains some of the key effects of the hormone testosterone — how it can amplify pre-existing tendencies for aggression or sexual behavior, but that it does not produce those behaviors per se. He also explains how testosterone impacts our social hierarchies, sense of confidence, and willingness to embrace challenges of different kinds. He also explains how our behaviors and perceptions shape testosterone levels. And we discuss estrogen and the powerful role it plays in brain development, health and longevity. Finally, we discuss free will, what it means to have free will, and if we have any free will, including how knowledge alone might allow us to make better decisions for ourselves and society.
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Links:
- Dr. Sapolsky's most recent book, "Behave: The Biology of Humans At Our Best & Worst": https://amzn.to/3yrZ6k7
- Support Research in the Huberman Lab at Stanford on Stress, Sleep & Human Performance: https://hubermanlab.stanford.edu/giving
Timestamps:
- 00:00:00 Introduction: Dr. Robert Sapolsky
- 00:02:26 Sponsors: Roka, Inside Tracker, Belcampo
- 00:06:30 Stress: Short & Long-Term, Good & Bad
- 00:09:11 Valence & Amygdala
- 00:11:00 Testosterone: Common Myths vs. Actual Truths
- 00:15:15 Behaviors that Affect Testosterone
- 00:17:20 Mindsets & Contexts that Affect Testosterone
- 00:20:28 How Finger Length Ratios Reflect Prenatal Hormone Levels
- 00:22:30 Aggression: Male-Female, Female-Male, & Female-Female
- 00:24:05 Testosterone: The Challenge Hypothesis
- 00:29:20 How Dopamine Impacts Testosterone & Motivation
- 00:32:32 Estrogen: Improves Brain & Longevity BUT TIMING IS KEY
- 00:39:40 Are Testosterone & Sperm Counts in Males Really Dropping?
- 00:42:15 Stress Mitigation & Our Sense of Control
- 00:51:35 How Best to Buffer Stress
- 00:57:04 Power of Perception, Choice & Individual Differences
- 01:00:32 Context-Setting, Prefrontal Cortex & Hierarchy
- 01:11:20 How Dr. Sapolsky Accomplishes Deep Thinking
- 01:13:17 Do We Have Free Will?
- 01:20:50 How to Apply Knowledge & Learning
- 01:23:44 Robert’s New Book: “Determined: The Science of Life Without Free Will”
- 01:28:27 Reflections, Support of Podcast, & Supporting Stress Research