What is it like to shadow Elon Musk for two years? To sit courtside as he builds a rocket? Or tears apart an engineer? Or couch surfs at the homes of billionaires? And how on earth do you make sense of it all? Walter Isaacson is the biographer of giants: DaVinci, Franklin, Doudna, Jobs...and now Musk, former enfante terrible, rocket launcher, electric car innovator, and Twitter—er, X—disruptor, to put it gently. In this four part series, author Evan Ratliff (Mastermind, Longform Podcast) sits down with Isaacson to draw out the behind-the-scenes stories of this epic biography, and what the writer has learned as an outsider inside Silicon Valley.
ON CRISPR Episode 1: Beginnings
Earlier this year, when the world learned the news of baby KJ successfully undergoing the first personalized genetic treatment, it represented a milestone for researchers and patients. But behind this scientific feat there’s the story of the technology that made it possible, CRISPR, and one of the key pioneers behind it — Jennifer Doudna.
Evan sits down with Walter Isaacson to understand how Doudna’s upbringing in Hilo, Hawaii influenced her trajectory as a gene editing scientist. And how the history of gene editing might have started with understanding DNA, but soon after, it became clear the real secret lay with its underrated sibling molecule, RNA.
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